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1.
Article in Spanish | LILACS, BINACIS | ID: biblio-1427219

ABSTRACT

Introducción: El absceso epidural espinal piógeno es la localización de una colección infecciosa dentro del canal raquídeo, por fuera del saco dural. El diagnóstico es difícil y las consecuencias son devastadoras a causa de la compresión o el compromiso vascular. La resonancia magnética tiene una alta sensibilidad y especificidad diagnósticas que aumentan si se administra un medio de contraste. Los objetivos de este estudio fueron: determinar la reproducibilidad inter- e intraobservador, y discriminar los distintos parámetros y diferencias entre especialidades. materiales y métodos: Veintisiete observadores independientes evaluaron 5 parámetros: región, ubicación, compromiso, asociación y perivertebral, absceso extravertebral anterior, lateral o posterior. Se analizaron 35 casos en tres oportunidades, se utilizó el coeficiente kappa. Resultados: El nivel de acuerdo global intra- e interobservador global fue kappa 0,76; los valores obtenidos fueron: región 0,94; ubicación 0,88; compromiso 0,55; asociación 0,67 y perivertebral 0,77. Los tres primeros parámetros dan noción de volumen y los dos últimos reflejan la presencia de focos infecciosos vertebrales por fuera del conducto. Conclusiones: La clasificación morfológica propuesta es de uso simple y tiene una muy buena tasa de reproducibilidad intra- e interobservador. Los parámetros con mayor reproducibilidad son: región y ubicación (>0,87). Nivel de Evidencia: III


Introduction: A pyogenic spinal epidural abscess is an infectious collection inside the spinal canal, outside the dural sac. The diagnosis is difficult and the consequences are devastating due to compression or vascular compromise. MRI has a high diagnostic sensitivity and specificity, which improves when a contrast medium is used. Objectives: To determine the inter- and intra-observer reproducibility, and to discriminate the different parameters and differences between specialties. Materials and methods: Twenty-seven independent observers evaluated 5 parameters: region, location, involvement, association, and perivertebral, anterior, lateral, or posterior extravertebral abscess. The kappa coefficient was used to analyze 35 cases on three occasions. Results: The overall intra- and inter-observer global agreement level is kappa 0.76, with the following values obtained: region 0.94; location 0.88; involvement 0.55; association 0.67 and perivertebral abscess 0.77. The first three parameters indicate volume, while the final two indicate the presence of vertebral infectious foci outside the canal. Conclusions: The proposed morphological classification is simple to use and has high intra- and inter-observer reproducibility. The most reproducible parameters are region and location (>0.87). Level of Evidence: III


Subject(s)
Osteomyelitis , Spinal Diseases , Discitis , Epidural Abscess , Infections
2.
Rev. chil. neuro-psiquiatr ; 59(3): 248-254, sept. 2021. ilus
Article in Spanish | LILACS | ID: biblio-1388394

ABSTRACT

INTRODUCCIÓN: El Tumor inflamatorio de Pott es una complicación rara de una patología frecuente, como son los cuadros infecciosos sinusales, cada vez más inusual por el uso extendido de antibióticos de amplio espectro, es más frecuente en la población adolescente por la neumatización similar al adulto. Se presenta como un aumento de volumen blando a nivel frontal con una osteomielitis del hueso frontal y un absceso subperióstico. MATERIALES Y MÉTODOS: En este trabajo, se presenta una revisión bibliográfica del tema y un caso de un paciente de 9 años, quien cursó con un cuadro infeccioso sinusal, que posterior desarrollo un aumento de volumen frontal, mostrando las imágenes perioperatorias e intraoperatorias. DISCUSIÓN Y CONCLUSIÓN: El absceso subperióstico secundario a la sinusitis, es una complicación rara. Sin embargo, se debe pensar en el diagnostico en pacientes de evolución tórpida y/o que presentan sintomatología neurológica, como convulsiones, se debe completar el estudio con neuroimagen contrastada.


INTRODUCTION: Pott's inflammatory tumor is a rare complication of a frequent pathology, such as sinus infections, increasingly unusual due to the use of broad-spectrum antibiotics, it is more frequent in the adolescent population due to pneumatization similar to that of adults. It presents as an increase in volume at a frontal level with osteomyelitis of the frontal bone and a subperiosteal abscess. ;MATERIAL AND METHODS: In this work, we present a bibliographic review and a case of a 9-year-old patient, who presented with an infectious sinus, which later developed an increase in frontal volume, the perioperative and intraoperative images are shown. DISCUSSION AND CONCLUSION: Subperiosteal abscess secondary to sinusitis is a rare complication. However, the diagnosis should be considered in patients with torpid evolution and / or who present neurological symptoms, such as seizures, the study must be completed with a contrast brain image.


Subject(s)
Humans , Male , Child , Pott Puffy Tumor/surgery , Pott Puffy Tumor/diagnostic imaging , Prognosis , Seizures , Sinusitis/complications , Magnetic Resonance Imaging , Tomography, X-Ray Computed , Craniotomy , Epidural Abscess , Pott Puffy Tumor/microbiology
5.
Acta otorrinolaringol. cir. cuello (En línea) ; 49(1): 53-56, 2021. ilus, tab, graf
Article in Spanish | LILACS, COLNAL | ID: biblio-1152170

ABSTRACT

Introducción: el absceso epidural posterolateral y la compresión radicular es una rara complicación del absceso retrofaríngeo (ARF). Se realizó el reporte de un caso con esta complicación extremadamente rara. Método: reporte de caso y revisión de la literatura (estudios radiológicos, historia y hallazgos clínicos). Se firmó consentimiento del paciente para la publicación. Resultados: paciente de 33 años remitido a nivel terciario de atención con un cuadro clínico de cervicalgia, odinofagia y fiebre. La tomografía axial computarizada (TAC) y la resonancia magnética nuclear (RMN) mostraron una colección retrofaríngea con compromiso epidural en el espacio medular cervical; en el examen físico se encontró odinofagia, cervicalgia, fiebre y pérdida de la fuerza muscular en el miembro superior derecho. El paciente fue llevado a manejo quirúrgico por otorrinolaringología y ortopedia para el drenaje de la colección; además, se le administró antibioticoterapia con cefepime y clindamicina por 21 días con buenos resultados; se consideró que el origen del absceso era idiopático. Conclusiones: el absceso epidural y la compresión radicular secundarias a un ARF es una rara y potencialmente mortal complicación de esta patología, con secuelas importantes en el paciente que la padece, que requiere un manejo médico-quirúrgico. En nuestro caso el manejo fue interdisciplinario, ya que integró otorrinolaringología, ortopedia, infectología y fisioterapia, lo que resultó en una evolución satisfactoria del paciente.


Introduction: posterolateral epidural abscess and radicular compression is a rare complication of retropharyngeal abscess (RFA), a case report with this extremely rare complication was made. Method: case report and review of the literature (radiological studies, clinical history, clinical findings) patient's consent was signed for the publication. Results: a 33-year-old patient referred at the tertiary care level with a clinical picture of cervicalgia, odynophagia and fever; CT and MRI showed retropharyngeal collection with epidural involvement in the cord cervical space, physical examination, odynophagia, cervicalgia, fever and loss of muscle strength in the right upper limb. Led to surgical management by ENT and orthopedics column for drainage of the collection; antibiotic therapy with cefepime, clindamycin for 21 days with good results; It was considered of idiopathic origin. Conclusions: epidural abscess and root compression secondary to an RFA is a rare and potentially fatal complication of this pathology with important sequelae in the patient, which requires medical-surgical management, in our case the management was integrated interdisciplinary otolaryngology, orthopedics, infectology, physiotherapy , with satisfactory evolution in the patient.


Subject(s)
Humans , Male , Adult , Spinal Cord , Staphylococcal Infections/complications , Retropharyngeal Abscess/complications , Epidural Abscess/etiology , Nerve Compression Syndromes/etiology , Staphylococcal Infections/therapy , Staphylococcal Infections/diagnostic imaging , Staphylococcus aureus/isolation & purification , Retropharyngeal Abscess/therapy , Retropharyngeal Abscess/diagnostic imaging , Epidural Abscess/therapy , Epidural Abscess/diagnostic imaging , Nerve Compression Syndromes/therapy , Nerve Compression Syndromes/diagnostic imaging
6.
Rev. Méd. Clín. Condes ; 31(5/6): 448-455, sept.-dic. 2020. ilus
Article in Spanish | LILACS | ID: biblio-1224138

ABSTRACT

Las infecciones espinales son cuadros clínicos poco frecuentes, que exigen un alto índice de sospecha. La prevalencia de infecciones piógenas de la columna ha ido en aumento, en parte debido al envejecimiento de la población y a un mayor número de pacientes inmunocomprometidos. El estudio imagenológico se puede iniciar con radiografías simples, pero la resonancia magnética es el examen imagenológico de elección, ya que puede dar resultados positivos de forma precoz, entregando información más detallada del compromiso vertebral y tejidos blandos adyacentes. Aunque la clínica y los hallazgos imagenológicos nos pueden orientar, es importante intentar un diagnóstico microbiológico tomando cultivos y muestras para identificar al agente causal antes de iniciar los antibióticos; aunque es óptimo un tratamiento agente-específico, hasta un 25% de los casos queda sin diagnóstico del agente. El tratamiento es inicialmente médico, con antibióticos e inmovilización, pero se debe considerar la cirugía en casos de compromiso neurológico, deformidad progresiva, inestabilidad, sepsis no controlada o dolor intratable. El manejo quirúrgico actual consiste en el aseo y estabilización precoz de los segmentos vertebrales comprometidos. Descartar una endocarditis concomitante y el examen neurológico seriado son parte del manejo de estos pacientes.


Spinal infections are unusual conditions requiring a high index of suspicion for clinical diagnosis. There has been a global increase in the number of pyogenic spinal infections due to an aging population and a higher proportion of immunocompromised patients. The imaging study should start with plain radiographs, but magnetic resonance imaging (mri) is the gold standard for diagnosis. Mri can detect bone and disc changes earlier than other methods, and it provides detailed information on bone and adjacent soft tissues. Blood cultures and local samples for culture and pathology should be obtained, trying to identify the pathogen. According to the result, the most appropriate drug must be selected depending on susceptibility and penetration into spinal tissues. Treatment should start with antibiotics and immobilization; surgery should be considered in cases with neurological impairment, progressive deformity, spine instability, sepsis, or non-controlled pain. Current surgical treatment includes debridement and early stabilization. Practitioners should rule out endocarditis and perform a serial neurological examination managing these patients.


Subject(s)
Humans , Spinal Diseases/diagnosis , Spinal Diseases/microbiology , Spinal Diseases/therapy , Prognosis , Spinal Diseases/physiopathology , Spine/microbiology , Spondylitis/diagnosis , Spondylitis/therapy , Discitis/diagnosis , Discitis/therapy , Epidural Abscess/diagnosis , Epidural Abscess/therapy
7.
Arch. argent. pediatr ; 118(2): e166-e169, abr. 2020. ilus
Article in Spanish | LILACS, BINACIS | ID: biblio-1100425

ABSTRACT

La mastoiditis aguda es una infección de las celdillas mastoideas, generalmente, secundaria a la progresión de una otitis media aguda. Las bacterias aisladas con más frecuencia en las mastoiditis son Streptococcus pneumoniae, Streptococcus pyogenes y Staphylococcus aureus. La infección mastoidea puede extenderse por contigüidad, afectar a estructuras vecinas y dar lugar a complicaciones intra- o extracraneales. Las más frecuentes son las intracraneales, entre las que se incluyen la meningitis, el absceso cerebeloso o del lóbulo temporal, el absceso epi- o subdural y la trombosis de senos venosos.Se presenta el caso de una niña de 4 años que desarrolló dos complicaciones intracraneales (absceso epidural y trombosis de senos venosos transverso y sigmoideo) a partir de una mastoiditis aguda producida por Streptococus pyogenes


Acute mastoiditis is an infection that affects the mastoid air-cell system, usually due to the progression of an acute otitis media. The bacteria most frequently isolated in acute mastoiditis are Streptococcus pneumoniae, Streptococcus pyogenes and Staphylococcus aureus. The mastoid infection can extend affecting contiguous structures and producing intra or extracranial complications. The most frequent ones are intracranial complications, including meningitis, temporal lobe or cerebellar abscess, epidural or subdural abscess and venous sinus thrombosis.We present the case of a 4-year-old girl who developed two intracranial complications (intracranial epidural abscess and transverse and sigmoid sinus thrombosis) initiated in an acute mastoiditis produced by Streptococcus pyogenes.


Subject(s)
Humans , Female , Child, Preschool , Sinus Thrombosis, Intracranial/diagnostic imaging , Streptococcus pyogenes , Epidural Abscess/diagnostic imaging , Mastoiditis/complications , Mastoiditis/drug therapy , Mastoiditis/diagnostic imaging
8.
Anesthesia and Pain Medicine ; : 95-101, 2019.
Article in English | WPRIM | ID: wpr-719396

ABSTRACT

BACKGROUND: The clinical outcomes and safety of thoracic epidural catheterization in anesthetized adult patients has not yet been established. The purpose of this study was to compare clinical differences between epidural catheterization performed before and after anesthesia for postoperative pain control. METHODS: The medical records of 549 patients who received thoracic epidural catheterization before (awake group, n = 303) or after (anesthetized group, n = 246) induction of anesthesia for major abdominal surgery were reviewed retrospectively. RESULTS: The catheter insertion time (1.6 ± 1.5 vs. 1.1 ± 1.2 min; 95% confidence interval [95% CI], 0.3–0.8; effect size, 0.368; P < 0.001) and number of attempts required for successful epidural catheterization (1 [1, 3] vs. 1 [1, 2], P = 0.003) were increased in the awake group. The incidence rates of dural puncture, vascular injury and postoperative paresthesia were similar between the two groups. The median surgical site numerical rating scale pain score (0 = no pain, 10 = worst pain imaginable) was lower in the awake group than in the anesthetized group (3 vs. 4 on postoperative day 1, P < 0.001; and 2 vs. 3 on postoperative day 3, P = 0.002). Serious complications, including meningitis, epidural abscess, epidural hematoma, spinal cord injury, and paraplegia, were not observed in either group. CONCLUSIONS: Successful epidural catheterization before induction of anesthesia required more attempts versus after anesthesia. Overall complication rates of thoracic epidural catheterization were similar regardless of the timing of the procedure.


Subject(s)
Adult , Humans , Analgesia, Epidural , Anesthesia , Catheterization , Catheters , Epidural Abscess , Hematoma, Epidural, Spinal , Incidence , Medical Records , Meningitis , Pain, Postoperative , Paraplegia , Paresthesia , Postoperative Complications , Punctures , Retrospective Studies , Vascular System Injuries
9.
Rev. Soc. Bras. Med. Trop ; 52: e20180243, 2019. graf
Article in English | LILACS | ID: biblio-1003126

ABSTRACT

Abstract Brucellosis, a zoonosis with worldwide distribution, is a systemic infection caused by bacteria of the genus Brucella. Meanwhile, brucellosis often causes complications, such as osteoarticular involvement, and spondylitis is the most prevalent and important clinical form. Here, is a case of cervical brucellar spondylitis causing incomplete limb paralysis in a middle-aged male. The diagnosis was based on clinical history, and supported by Brucella serology and magnetic resonance imaging. Quadruple antibacterial treatment continued for four weeks. In this case, the epidural abscess causing spinal cord compression resolved without surgery. In addition, the patient had recovered from most of the neurologic deficits.


Subject(s)
Humans , Male , Paralysis/etiology , Spondylitis/diagnosis , Brucellosis/diagnosis , Epidural Abscess/etiology , Spondylitis/complications , Brucellosis/complications , Magnetic Resonance Imaging , Cervical Vertebrae , Middle Aged
10.
Rev chil anest ; 48(5): 409-411, 2019.
Article in Spanish | LILACS | ID: biblio-1509945

ABSTRACT

INTRODUCTION: The presence of an active bacteremia has been considered a relative contraindication to perform an intrathecal puncture due to the risk of causing meningitis or epidural abscess. However, a clear and definite causal relationship has not yet been demonstrated. OBJECTIVES: To determine the relationship between intrathecal puncture and the development of meningitis in sub-jects with bacteremia. MATERIALS AND METHODS: Experimental study in rats with chronic bacteremia to which dural puncture was performed. Meningitis was then evaluated by direct drainage of the cisterna magna and histopathological studies of brain tissue. RESULTS AND CONCLUSION: 12 of 40 bacteremic rats that underwent intrathecal puncture developed meningitis. Previous administration of antibiotics seems to reduce this risk.


INTRODUCCIÓN: Se ha considerado la presencia de una bacteremia activa como contraindicación relativa para realizar una punción intratecal por el riesgo de provocar meningitis o absceso peridural. Sin embargo, aún no se ha podido demostrar una relación causal clara y definida. OBJETIVOS: Determinar la relación entre punción intratecal y el desarrollo de meningitis en sujetos con bacteremia. MATERIALES Y MÉTODOS: Estudio experimental en ratas con bacteremia crónica a las que se les realizó punción dural, luego se evaluó la presencia o no de meningitis mediante drenaje directo de la cisterna magna y estudios histopatológicos de tejido cerebral. RESULTADOS Y CONCLUSIÓN: 12 de 40 ratas bacterémicas a las que se le realizó punción intratecal desarrollaron meningitis. La adminis-tración previa de antibiótico parece disminuir este riesgo.


Subject(s)
Animals , Rats , Spinal Puncture/adverse effects , Meningitis, Bacterial/etiology , Bacteremia/complications , Epidural Abscess/etiology , Anesthesia, Spinal/adverse effects , Reproducibility of Results , Rats, Sprague-Dawley , Contraindications
11.
Yonsei Medical Journal ; : 1103-1107, 2019.
Article in English | WPRIM | ID: wpr-762048

ABSTRACT

The incidence of vaccine-type Streptococcus pneumoniae carriage and disease have declined in vaccinated children as well as in unvaccinated children and adults. However, diseases caused by non-vaccine type (NVT) S. pneumoniae are increasing. In this study, we report an invasive pneumococcal disease (IPD) caused by NVT multidrug-resistant (MDR) S. pneumoniae transmitted from a vaccinated infant to an unvaccinated healthy woman, and the clinical characteristics of this serotype. A 29-year-old previously healthy woman visited our hospital with fever and headache. She had been breastfeeding her baby for 8 months. She was diagnosed with brain abscess and sinusitis caused by S. pneumoniae. Although the patient had no previous exposure to antibiotics, antibiotic susceptibility test identified the pathogen as MDR. The patient's family members were examined using nasopharyngeal swabs for bacterial culture. The serotype of S. pneumoniae identified from the blood, abscess, and sputum of the patient was 15B/C. After investing the patient's family members, we found that the serotype from nasopharyngeal specimen of her baby was the same. We described an invasive MDR pneumococcal disease in an immunocompetent young adult in the community. IPD likely spread to the patient by close contact with her baby, who harbored S. pneumoniae of NVT. The spread of NVT S. pneumoniae in the post-vaccine era has increased in the community, and resistance pattern for S. pneumoniae of 15B/C changed compared to the pre-pneumococcal conjugate vaccine era. The spread of MDR pathogens causing IPD among family members should be monitored.


Subject(s)
Adult , Child , Female , Humans , Infant , Young Adult , Abscess , Anti-Bacterial Agents , Brain Abscess , Breast Feeding , Epidural Abscess , Fever , Headache , Incidence , Pneumonia , Serogroup , Sinusitis , Sputum , Streptococcus pneumoniae , Streptococcus , Vaccination
12.
Asian Spine Journal ; : 608-614, 2019.
Article in English | WPRIM | ID: wpr-762967

ABSTRACT

STUDY DESIGN: Retrospective cohort study. PURPOSE: To describe our experience in the management and outcomes of vertebral column osteomyelitis (VCO), particularly focusing on the risk factors of early and late mortality. OVERVIEW OF LITERATURE: Previous reports suggest a global increase in spinal column infections highlighting significant morbidity and mortality. To date, there have been no reports from our local population, and no previous report has assessed the potential relationship of frailty with mortality in a cohort of patients with VCO. METHODS: We reviewed 76 consecutive patients with VCO between 2009 and 2016 in Waikato Hospital, New Zealand. Demographic, clinical, microbiological, and treatment data were collected. Comorbidities were noted to calculate the modified Frailty Index (mFI). Mortality at 30 days and 1 year was recorded. Univariate and multivariate analyses were used to identify the predictors of mortality. RESULTS: The mean age of patients was 64.1 years, with 77.6% being male. Most patients presented with axial back pain (71.1%), with the lumbar spine most commonly affected (46%). A mean of 2.1 vertebral bodies was involved. Methicillin-sensitive Staphylococcus aureus was the most common organism of infection (35.5%), and 15.8% of patients exhibited polymicrobial infection. Twenty patients (26.3%) underwent surgical intervention, which was more likely in patients with concomitant spinal epidural abscess (odds ratio [OR], 4.88) or spondylodiscitis (OR, 3.81). Mortality rate was 5.2% at 30 days and 22.3% at 1 year. The presence of frailty (OR, 13.62) and chronic renal failure (OR, 13.40) elevated the 30-day mortality risk only in univariate analysis. An increase in age (OR, 1.07) and the number of vertebral levels (OR, 2.30) elevated the 1-year mortality risk in both univariate and multivariate analyses. CONCLUSIONS: Although the mFI correlated with 30-day mortality in univariate analysis, it was not a significant predictor in multivariate analysis. An increase in age and the number of levels involved elevated the 1-year mortality risk.


Subject(s)
Adult , Humans , Male , Back Pain , Cohort Studies , Coinfection , Comorbidity , Discitis , Epidural Abscess , Kidney Failure, Chronic , Mortality , Multivariate Analysis , New Zealand , Osteomyelitis , Retrospective Studies , Risk Factors , Spine , Staphylococcus aureus
13.
Archives of Craniofacial Surgery ; : 332-335, 2019.
Article in English | WPRIM | ID: wpr-762790

ABSTRACT

Cellulitis, one of most common diseases of everyday life, is often overlooked for its significance. Although cellulitis does not cause or lead to serious problems usually, its possibility to cause life-threatening problem should be known. In present case, a patient who had received acupuncture treatment a week earlier presented to the clinic with symptoms of facial cellulitis. The disease resolved within few weeks under empirical antibiotic treatment but recurred after 3 months. Under close history review of the patient, we found out that the patient had received craniectomy 20 years ago. The patient had blunt headache with no other neurological symptoms that could suspect cranial infection, but considering the risk originating from the patient’s surgical history, brain computed tomography (CT) was taken. CT images revealed abscess formation in the subgaleal and epidural spaces. Craniotomy with abscess evacuation was done promptly. With additional antibiotic treatment postoperatively, the disease resolved, and the 1-month postoperative follow-up brain CT showed no signs of abscess formation.


Subject(s)
Humans , Abscess , Acupuncture , Brain , Cellulitis , Craniotomy , Empyema , Epidural Abscess , Epidural Space , Follow-Up Studies , Headache
14.
Pediatric Infection & Vaccine ; : 112-117, 2019.
Article in English | WPRIM | ID: wpr-760895

ABSTRACT

Eikenella corrodens rarely causes invasive head and neck infections in immunocompetent children. We report a case of epidural abscess caused by E. corrodens in a previously healthy 13-year-old boy who presented with fever, headache, and vomiting. On physical examination upon admission, there was no neck stiffness, but discharge from the right ear was observed. Brain magnetic resonance imaging (MRI) revealed approximately 4.5-cm-sized epidural empyema on the right temporal lobe as well as bilateral ethmoid and sphenoid sinusitis, right mastoiditis, and right otitis media. During treatment with vancomycin and cefotaxime, purulent ear discharge aggravated, and on follow-up brain MRI, the empyema size increased to 5.6×3.4 cm with interval development of an abscess at the right sphenoid sinus. Burr hole trephination was performed, and foul-smelling pus was aspirated from the epidural abscess near the right temporal lobe. Pus culture yielded E. corrodens. Endoscopic sphenoidotomy was also performed with massive pus drainage, and the same organism was grown. The patient was treated with intravenous cefotaxime for 3 weeks and recovered well with no other complications. Therefore, E. corrodens can cause serious complications in children with untreated sinusitis.


Subject(s)
Adolescent , Child , Humans , Male , Abscess , Brain , Cefotaxime , Drainage , Ear , Eikenella corrodens , Eikenella , Empyema , Epidural Abscess , Fever , Follow-Up Studies , Head , Headache , Magnetic Resonance Imaging , Mastoid , Mastoiditis , Neck , Otitis Media , Physical Examination , Sinusitis , Sphenoid Sinus , Sphenoid Sinusitis , Suppuration , Temporal Lobe , Trephining , Vancomycin , Vomiting
15.
Korean Journal of Neurotrauma ; : 20-23, 2018.
Article in English | WPRIM | ID: wpr-713926

ABSTRACT

OBJECTIVE: Acute hemiparesis is often an early presentation of acute ischemic stroke, though it can occur in various disorders. This study aimed to investigate the improper use of thrombolytic agents for patients with acute hemiparesis, following the misdiagnosis of acute ischemic stroke. METHODS: We analyzed the clinical and radiological data of nine patients initially misdiagnosed with cerebral stroke in the emergency room from May 2013 to January 2017. All the patients were treated with tissue plasminogen activator (TPA) owing to the presence of acute hemiparesis. Subsequently, emergent computed tomography scan showed no intracranial hemorrhage. Clinical findings including neurological deficits, clinical course, and related complications were detected and analyzed. RESULTS: Acute hemiparesis was observed in the following conditions: spontaneous spinal epidural hematoma, Brown-Séquard syndrome caused by cervical disc herniation, cervical epidural abscess, hypoglycemia in the presence of an old stroke, and seizure or convulsion disorder. Although acute hemiparesis was regarded as a contraindication, inappropriate TPA administration did not aggravate the neurological condition in any of the patients who required surgery. CONCLUSION: Upon presentation of acute hemiparesis, various conditions mimicking cerebral stroke should be considered to avoid misdiagnosis. We suggest that physicians should exercise caution when prescribing thrombolytic agents.


Subject(s)
Humans , Diagnostic Errors , Emergency Service, Hospital , Epidural Abscess , Fibrinolytic Agents , Hematoma, Epidural, Spinal , Hypoglycemia , Intracranial Hemorrhages , Paresis , Seizures , Stroke , Tissue Plasminogen Activator
16.
Journal of Korean Society of Spine Surgery ; : 18-23, 2018.
Article in Korean | WPRIM | ID: wpr-765596

ABSTRACT

STUDY DESIGN: Case report OBJECTIVES: We report a case of surgically proven tophaceous gout of the lumbar spine at the L5-S1 level in a 43-year-old man that mimicked infectious spondylodiscitis and epidural abscess on magnetic resonance (MR) images. SUMMARY OF LITERATURE REVIEW: Some patients have chronic back pain with an epidural mass. Among the many causes of epidural masses, tophaceous gout of the lumbar spine is very rare. MATERIALS AND METHODS: A 43-year-old man presented with fever and chronic back pain with radiating pain. In an MR image of L4-5, an abnormal subcutaneous mass was found in the posterior epidural space. The subcutaneous mass was isointense on T1-weighted images compared with the intervertebral disc, and focally and strongly hyperintense and heterogeneous on T2-weighted images. After the intravenous administration of gadolinium contrast, the mass was fairly homogenous, with a low signal intensity and without enhancement. With the diagnosis of infective spondylitis with epidural abscess, we performed a decompressive mass resection. RESULTS: The pathologic examination revealed multinuclear giant cells and amorphous crystalline fibrous tissue. The lesion was diagnosed as tophaceous gout. CONCLUSIONS: This case underscores the importance of considering tophaceous gout in the differential diagnosis of an epidural mass in a patient with chronic back pain.


Subject(s)
Adult , Humans , Administration, Intravenous , Back Pain , Crystallins , Diagnosis , Diagnosis, Differential , Discitis , Epidural Abscess , Epidural Space , Fever , Gadolinium , Giant Cells , Gout , Intervertebral Disc , Magnetic Resonance Imaging , Spine , Spondylitis
17.
Arch. argent. pediatr ; 115(3): 146-149, jun. 2017. ilus
Article in Spanish | LILACS, BINACIS | ID: biblio-887324

ABSTRACT

El absceso epidural espinal, una patología poco frecuente, presenta una incidencia de un caso cada 100 000 individuos, y se observa un aumento debido al incremento de factores de riesgo, tales como diabetes mellitus, anomalías espinales, tatuajes, acupuntura, analgesia epidural, sumado a una mayor disponibilidad de métodos de imágenes. Es una colección purulenta localizada entre la duramadre y el canal medular. Los gérmenes más comunes son Staphylococcus aureus y bacterias Gram-negativas. Sin tratamiento oportuno, evoluciona a la compresión medular y secuelas neurológicas permanentes. Una niña de 11 años se presentó con fiebre de 48 horas de evolución, dolor lumbar izquierdo, marcha antálgica con envaramiento lumbar. El examen neurológico era normal. Sobre los miembros inferiores, se observaban lesiones ampollares destechadas. La resonancia nuclear magnética mostró una imagen compatible con absceso epidural espinal. Evolucionó favorablemente. El tratamiento consistió en drenaje quirúrgico y antibióticos por 6 semanas. Del cultivo del material obtenido, creció Staphylococcus aureus meticilino sensible.


Spinal epidural abscess is an uncommon pathology. It has an incidence of one case per 100 000 individuals. An increase is observed due to the raise of risk factors such as diabetes mellitus, spinal abnormalities, tattoos, acupuncture, epidural analgesia, and a greater availability of imaging methods. It is a purulent collection located between the dura and the medullary canal. The most common germs are Staphylococcus aureus and Gram-negative bacteria. Without timely treatment, it evolves to medullary compression and permanent neurological sequelae. An 11-year-old girl was admitted with fever of 48 hs evolution, left lower back pain, antalgic gait with lumbar stiffness. Neurological examination was normal. Blunt blistering lesions were observed on lower limbs. Magnetic resonance imaging showed an image compatible with spinal epidural abscess. The evolutionwas favorable. Treatment consisted of surgical drainage and antibiotics for 6 weeks. From the culture of the material obtained, methidllin-sensitive Staphylococcus aureus was isolated.


Subject(s)
Humans , Female , Child , Spinal Cord Diseases/microbiology , Staphylococcal Infections/diagnosis , Staphylococcal Infections/drug therapy , Epidural Abscess/diagnosis , Epidural Abscess/drug therapy , Spinal Cord Diseases/diagnosis , Spinal Cord Diseases/drug therapy
18.
Rev. Assoc. Med. Bras. (1992) ; 63(1): 18-20, Jan. 2017. graf
Article in English | LILACS | ID: biblio-842521

ABSTRACT

Summary Spondylodiscitis affecting the cervical spine is the most unusual type. Disease progression can be dramatic, even causing quadriplegia and death. We present an unusual case that progressed with osteolytic lesions between C2 and C3, causing cord compression and epidural abscess. The patient was treated surgically by a double approach and improved without neurological deficits and with better inflammatory markers. We reviewed the current literature on the subject.


Resumo A espondilodiscite, que acomete a coluna cervical, é a de localização mais rara. Pode ter uma evolução dramática, inclusive causando tetraplegia e óbito. Apresentamos um caso atípico que evoluiu com lesões osteolíticas entre C2 e C3, causando compressão medular e abscesso epidural. O paciente foi submetido a tratamento cirúrgico por dupla abordagem e evoluiu bem, sem déficits neurológicos e com melhora dos marcadores inflamatórios. Revisamos a literatura vigente sobre o assunto.


Subject(s)
Humans , Male , Spondylitis/diagnostic imaging , Staphylococcal Infections/complications , Staphylococcus aureus , Discitis/diagnostic imaging , Cervical Vertebrae/microbiology , Spinal Cord Compression/etiology , Spondylitis/complications , Spondylitis/microbiology , Staphylococcal Infections/diagnosis , Magnetic Resonance Imaging , Discitis/complications , Discitis/microbiology , Tomography, X-Ray Computed , Epidural Abscess/etiology , Middle Aged
19.
Rev. chil. radiol ; 23(2): 66-76, 2017. ilus, tab
Article in Spanish | LILACS | ID: biblio-900108

ABSTRACT

Disc herniation is a frequent pathology in the radiologist's daily practice. There are different pathologies that can simulate a herniated disc from the clinical and especially the imaging point of view that we should consider whenever we report a herniated disc. These lesions may originate from the vertebral body (osteophytes and metastases), the intervertebral disc (discal cyst), the intervertebral foramina (neurinomas), the interapophyseal joints (synovial cyst) and from the epidural space (hematoma and epidural abscess).


La hernia discal es una patología frecuente en la práctica diaria del radiólogo. Hay distintas patologías que pueden simular una hernia discal desde el punto de vista clínico y especialmente imagenológico que debemos considerar cada vez que informamos una hernia discal. Estas lesiones pueden provenir del cuerpo vertebral (osteofitos y metástasis), del disco intervertebral (quiste discal), de los forámenes intervertebrales (neurinomas), de las articulaciones interapofisiarias (quiste sinovial) y desde el espacio epidural (hematoma y absceso epidural).


Subject(s)
Humans , Magnetic Resonance Spectroscopy/statistics & numerical data , Intervertebral Disc Displacement/diagnosis , Synovial Cyst/diagnostic imaging , Epidural Abscess/diagnosis , Intervertebral Disc Displacement/diagnostic imaging
20.
The Journal of the Korean Orthopaedic Association ; : 359-363, 2017.
Article in Korean | WPRIM | ID: wpr-648256

ABSTRACT

Spinal infection due to Serratia marcescens is very rare. A 78-year-old male patient withoutany risk factor was admitted to our hospital with chief complaints of severe back pain, fever, weakness in both legs, and bowel dysfunction, following caudal epidural injection. Magnetic resonance imaging revealed spondylodiscitis with epidural abscess. Surgical decompression was performed and the epidural abscess was removed. The cultures isolated S. marcescens, which can cause nosocomial infection in immunocompromised patient. However, to the best of our knowledge, we report the first case of S. marcescens spinal epidural abscess following epidural injection, with literature review.


Subject(s)
Aged , Humans , Male , Back Pain , Cross Infection , Decompression, Surgical , Discitis , Epidural Abscess , Fever , Immunocompromised Host , Injections, Epidural , Leg , Magnetic Resonance Imaging , Risk Factors , Serratia marcescens , Serratia
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